PZ15527
PZ15527 is a proteolysis-targeting chimera (PROTAC) molecule designed to selectively degrade Bcl-xL. It serves as a chemical probe for studying Bcl-xL biology and apoptosis in cancer research, with utility demonstrated in both cellular and in vivo models.
Product Specifications
Field of Research
Pharmacology & Drug Discovery
Smiles
O=C1N (C2C (NC (CC2) =O) =O) C (C (C1=CC=C3) =C3NCCOCCOCC4=CN (CCCC (N5CCN (CC[C@H] (CSC6=CC=CC=C6) NC7=C (S (=O) (C (F) (F) F) =O) C=C (S (NC (C8=CC=C (N9CCN (CC%10=C (C%11=CC=C (Cl) C=C%11) CCC (C) (C) C%10) CC9) C=C8) =O) (=O) =O) C=C7) CC5) =O) N=N4) =O
Molecular Formula
C71H82ClF3N12O12S3
Molecular Weight
1484.13
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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