ADEP-14
ADEP-14 is an acyldepsipeptide antibiotic that activates the bacterial ClpP protease, leading to uncontrolled proteolysis and degradation of essential proteins like FtsZ. This mechanism, studied in vitro and in vivo against Gram-positive pathogens, makes it a valuable research tool for investigating novel antibacterial strategies and bacterial cell division.
Product Specifications
Smiles
O=C ([C@H] (C) NC1=O) N2C[C@H] (C) C[C@@]2 ([H]) C (O[C@@H] (C) [C@H] (NC ([C@H] (CC3=CC (F) =CC (F) =C3) NC (/C=C/C=C/CCC) =O) =O) C (N4[C@@] (C (N5[C@@]1 ([H]) CCCC5) =O) ([H]) CCC4) =O) =O
Molecular Formula
C41H54F2N6O8
Molecular Weight
796.9
Storage Conditions
-20°C
Notes
For research use only.
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