Pomalidomide-methylamino-PEG1-NH2 hydrochloride
This compound serves as a versatile building block for PROTAC and molecular glue development, featuring a CRBN-binding pomalidomide moiety connected via a PEG linker to a terminal amine. The reactive amine enables conjugation to target warheads, facilitating the creation of bifunctional degraders for both in vitro and in vivo target validation studies.
Product Specifications
Field of Research
Pharmacology & Drug Discovery, Pharmacology & Drug Discovery; Cell Biology
Smiles
O=C (NC1=CC=CC (C (N2C (CC3) C (NC3=O) =O) =O) =C1C2=O) CCN (CCOCCN) C.[H]Cl
Molecular Formula
C21H28ClN5O6
Molecular Weight
481.93
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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