KG-548
KG-548 is a small molecule research compound that functions as a dual inhibitor of ARNT/TACC3 and HIF-1α. It disrupts HIF-2 dimerization and coactivator binding, suppressing lactate production. This inhibitor is a valuable tool for investigating cancer metabolism and tumor hypoxia in both in vitro and in vivo models.
Product Specifications
CAS Number
175205-09-1
Product Name Alternative
KG548
Field of Research
Cardiovascular Research, Epigenetics & Chromatin, Metabolism Research, Signal Transduction
Purity
99.62% (May vary between batches)
Solubility
DMSO:80 mg/mL (283.54 mM)
Smiles
FC (F) (F) C1=CC (=CC (=C1) C (F) (F) F) C2=NN=NN2
Molecular Formula
C9H4F6N4
Molecular Weight
282.15
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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