APL-1081 Antibody

APL-1081 (Mal-Exo-EVC-MMAE) is a linker-payload complex for constructing antibody-drug conjugates (ADCs) . It features the protease-cleavable Mal-Exo-EEVC linker conjugated to the cytotoxic agent MMAE, a potent microtubule inhibitor. This compound is utilized in ADC research for evaluating drug delivery and efficacy in both in vitro and in vivo cancer models.

Product Specifications

CAS Number

2921735-80-8

Field of Research

Metabolism Research

Smiles

[C@H] ([C@H] (C (N[C@@H] ([C@@H] (O) C1=CC=CC=C1) C) =O) C) (OC) [C@]2 (N (C (C[C@H] ([C@@H] (N (C ([C@@H] (NC ([C@@H] (N (C (OC (C (NCCCCCN3C (=O) C=CC3=O) =O) C4=CC=C (NC ([C@@H] (NC ([C@@H] (NC ([C@H] (CCC (O) =O) NC (C) =O) =O) [C@@H] (C) C) =O) CCCNC (N) =O) =O) C=C4) =O) C) C (C) C) =O) [C@@H] (C) C) =O) C) [C@H] (CC) C) OC) =O) CCC2) [H]