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Sitamaquine hydrochloride

Sitamaquine hydrochloride (WR 6026) is an oral 8-aminoquinoline antileishmanial agent. Its lipophilic weak base nature promotes accumulation in parasitic acidocalcisomes, where it inhibits mitochondrial complex II (succinate dehydrogenase) . This compound has been investigated in both in vitro assays and clinical trials for visceral leishmaniasis.

Product Specifications

CAS Number

5330-29-0

Field of Research

Immunology & Inflammation, Infectious Disease & Virology, Metabolism Research, Neuroscience, Pharmacology & Drug Discovery

Smiles

COC1=CC2=C (C) C=CN=C2C (NCCCCCCN (CC) CC) =C1.Cl.Cl

Molecular Formula

C21H35Cl2N3O

Molecular Weight

416.43

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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