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TMX-3013

TMX-3013 is a potent multi-CDK inhibitor with low nM IC50 values against CDK1, CDK2, CDK4, CDK5, and CDK6. It serves as a warhead for synthesizing CRBN-directed PROTAC degraders using a PEG linker, facilitating research into cell cycle regulation and targeted protein degradation in cancer models.

Product Specifications

CAS Number

2488761-18-6

Field of Research

Cell Biology, Signal Transduction

Smiles

O=C (N) C=1C (F) =CC=CC1NC2=NC (=NC=C2Br) NC3=CC=C (C=C3) S (=O) (=O) N

Molecular Formula

C17H14BrFN6O3S

Molecular Weight

481.3

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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