TMX-3013
TMX-3013 is a potent multi-CDK inhibitor with low nM IC50 values against CDK1, CDK2, CDK4, CDK5, and CDK6. It serves as a warhead for synthesizing CRBN-directed PROTAC degraders using a PEG linker, facilitating research into cell cycle regulation and targeted protein degradation in cancer models.
Product Specifications
CAS Number
2488761-18-6
Field of Research
Cell Biology, Signal Transduction
Smiles
O=C (N) C=1C (F) =CC=CC1NC2=NC (=NC=C2Br) NC3=CC=C (C=C3) S (=O) (=O) N
Molecular Formula
C17H14BrFN6O3S
Molecular Weight
481.3
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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