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DNA crosslinker 6

DNA crosslinker 6 (compound 1) is a potent anti-mitotic agent that selectively targets AT-rich DNA sequences, disrupting AT-hook protein binding (IC50=0.03 μM) . It also demonstrates anti-protozoal efficacy against Trypanosoma brucei (EC50=0.83 μM), making it a valuable tool for studying DNA-protein interactions and parasitic diseases in biochemical and cellular assays.

Product Specifications

CAS Number

272791-87-4

Field of Research

Infectious Disease & Virology, Neuroscience, Pharmacology & Drug Discovery

Smiles

O=C (NC1=CC=C (C=C1) NC2=NCCN2) C3=CC=C (C=C3) NC4=NCCN4

Molecular Formula

C19H21N7O

Molecular Weight

363.42

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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