BIO-2007817
BIO-2007817 is a potent positive allosteric modulator (PAM) of the E3 ubiquitin ligase Parkin, exhibiting an EC50 of 0.17 μM. It enhances wild-type Parkin activity, promotes its autoubiquitination, and increases mono-ubiquitinated Miro1. This small molecule is a valuable research tool for studying Parkin function in Parkinson's disease models, both in vitro and in vivo.
Product Specifications
Field of Research
Cell Biology, Infectious Disease & Virology, Molecular Biology, Protein Biochemistry, Signal Transduction
Molecular Formula
C32H36N6O3
Molecular Weight
552.67
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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