CQ-16
CQ-16 is an orally bioavailable small molecule drug conjugate (SMDC) targeting PSMA with high selectivity for PSMA-positive prostate cancer cells. It also functions as a potent PARP inhibitor (IC50=1 nM), supporting its investigation in targeted therapy and combination strategies for prostate cancer research in both cellular and animal models.
Product Specifications
CAS Number
3024354-59-1
Field of Research
Epigenetics & Chromatin, Immunology & Inflammation, Molecular Biology, Pharmacology & Drug Discovery
Smiles
C (=O) (C1 (NC (CCC (NCCCC[C@H] (NC (N[C@@H] (CCC (O) =O) C (O) =O) =O) C (O) =O) =O) =O) CC1) N2CCN (C (=O) C3=CC (CC=4C=5C (C (=O) NN4) =CC=CC5) =CC=C3F) CC2
Molecular Formula
C40H47FN8O12
Molecular Weight
850.85
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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Glutathione Peroxidase 4, CT (GPX4, GPX-4, GSHPx-4, Phospholipid Hydroperoxide Glutathione Peroxidase Mitochondrial, mtPHGPx, PHGPx, MGC103187, MGC118087, Phospholipid Hydroperoxidase, Sperm Nucleus Glutathione Peroxidase, snGPx, snPHGPx) discontinued
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