IL-1 beta, Cavia porcellus (His)
Product Specifications
UNSPSC Description
IL-1 beta is a potent proinflammatory cytokine expressed by monocytes, macrophages, and dendritic cells. IL-1 beta plays a key role in inflammation and immunologic reactions[1][2]. IL-1 beta Protein, Cavia porcellus (His) is produced in E. coli with six C-Terminal His-tags. It consists of 152 amino acids (T115-S266).
Type
Recombinant Proteins
Assay Protocol
https://www.medchemexpress.com/cytokines/il-1-beta-protein-cavia-porcellus-his.html
Purity
95.0
Smiles
TPVPSRNCTL HDIQHKRLVL SDPCELKALH LNGDNLNRQV VFSMSFVQGE RSDNKMPVAL GLKGKNLYLS CVMKDGKPVL QLESVDGKQY PKKKMEKRFV FNKITSKSTV EFESAQFPNW YISTSQAEHK PVFLGNNNGQ DIIDFKLELV SS
Molecular Weight
16-19 kDa
References & Citations
[1]Jan Petrasek, et al. IL-1 receptor antagonist ameliorates inflammasome-dependent alcoholic steatohepatitis in mice. J Clin Invest. 2012 Oct;122(10):3476-89.|[2]Karina Zitta, et al. Interleukin-1beta regulates cell proliferation and activity of extracellular matrix remodelling enzymes in cultured primary pig heart cells. Biochem Biophys Res Commun. 2010 Sep 3;399(4):542-7.|[3]Kenichi Shimada, et al. Caspase-1 dependent IL-1β secretion is critical for host defense in a mouse model of Chlamydia pneumoniae lung infection. PLoS One. 2011;6(6):e21477.
Shipping Conditions
Blue Ice
Storage Conditions
Stored at -20°C for 2 years
Available Sizes
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