NMDAR antagonist 2
NMDAR antagonist 2 (compound 3I) is a brain-penetrant NMDA receptor blocker with voltage-dependent inhibition, showing IC50 values of 4.42 μM at -60 mV and 214.75 μM at 40 mV for GluN1/GluN2A receptors. It has demonstrated neuroprotective effects, such as reducing hippocampal damage in research models, making it a tool for studying excitotoxicity and neurological disorders.
Product Specifications
Field of Research
Neuroscience, Neuroscience; Pharmacology & Drug Discovery, Pharmacology & Drug Discovery
Molecular Formula
C17H20ClNO
Molecular Weight
289.8
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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