Nrf2 activator 17
Compound 10 (Nrf2 activator 17) is a potent small molecule Nrf2 agonist with sub-picomolar activity in disrupting the Keap1-Nrf2 interaction. It activates the Nrf2 pathway in HepG2 cells with an EC50 below 10 μM, making it a valuable research tool for studying oxidative stress and cytoprotection in both cellular and animal models.
Product Specifications
CAS Number
3059044-55-9
Field of Research
Immunology & Inflammation, Neuroscience
Smiles
O=C (O) CC1C2=CC=C3C (=C2) CN (C (=O) N4CCC (OCCCCN5N=NC=6C5=CC=C1C6C) CC4) CC3
Molecular Formula
C29H35N5O4
Molecular Weight
517.62
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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