ADWX 1 TFA

ADWX 1 TFA is a potent and selective Kv1.3 channel inhibitor (IC50 = 1.89 pM) that suppresses calcium signaling and NF-κB activation. It ameliorates disease in EAE rat models, making it a valuable research tool for studying T-cell-mediated autoimmune diseases in both in vitro and in vivo contexts.