BTK ligand 12
BTK ligand 12 is a PROTAC-based ligand targeting Bruton's tyrosine kinase (BTK), designed to serve as an active control compound for BTK degraders like NRX-0492. It is a valuable tool for in vitro and in vivo studies in oncology and autoimmune disease research to validate degrader mechanisms and off-target effects.
Product Specifications
CAS Number
1791402-91-9
Field of Research
Cardiovascular Research, Cell Biology, Pharmacology & Drug Discovery, Protein Biochemistry, Signal Transduction
Purity
99.93% (May vary between batches)
Solubility
DMSO:10 mg/mL (20.89 mM)
Smiles
N (C=1N=C (C=NC1C (N) =O) N2C[C@@H] (CCC2) N3C (=O) N (C) CC3) C4=CC=C (C=C4) C5CCNCC5
Molecular Formula
C25H34N8O2
Molecular Weight
478.59
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
![Caspase 1 (CASP1) Rabbit Monoclonal Antibody [Clone ID: OTIR2E3]](https://cdn.genprice.uk/products/937/68dd1b74061270361ea1977d/imageurl/ta594222s.webp)
TA594222S 30 µL
Caspase 1 (CASP1) Rabbit Monoclonal Antibody [Clone ID: OTIR2E3]
Sign In for Pricing
View Details 
15670114 3x 1.0 µg
Cdh4 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Mouse)
Sign In for Pricing
View Details 
R13657h 1 Each
Human HAVCR2 / Hepatitis A virus cellular receptor 2 Recombinant Protein
Sign In for Pricing
View Details