BTK ligand 12
BTK ligand 12 is a PROTAC-based ligand targeting Bruton's tyrosine kinase (BTK), designed to serve as an active control compound for BTK degraders like NRX-0492. It is a valuable tool for in vitro and in vivo studies in oncology and autoimmune disease research to validate degrader mechanisms and off-target effects.
Product Specifications
CAS Number
1791402-91-9
Field of Research
Cardiovascular Research, Cell Biology, Pharmacology & Drug Discovery, Protein Biochemistry, Signal Transduction
Purity
99.93% (May vary between batches)
Solubility
DMSO:10 mg/mL (20.89 mM)
Smiles
N (C=1N=C (C=NC1C (N) =O) N2C[C@@H] (CCC2) N3C (=O) N (C) CC3) C4=CC=C (C=C4) C5CCNCC5
Molecular Formula
C25H34N8O2
Molecular Weight
478.59
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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