STAT3 HiBiT degrader 1
STAT3HiBiT degrader 1 is a highly potent small molecule that effectively degrades STAT3HiBiT fusion proteins, demonstrating a DC50 below 50 nM in A549 lung carcinoma cells. This tool compound is valuable for in vitro studies investigating STAT3-dependent signaling pathways in oncology and immunology research.
Product Specifications
CAS Number
2767166-30-1
Field of Research
Cancer Biology, Infectious Disease & Virology, Signal Transduction, Stem Cell & Developmental Biology
Smiles
O=C1N (C=2C (N1C) =CC (C#CCCC3CCN (C ([C@H] (CC4=CC (F) =C (F) C=C4) NC ([C@@H] (NC (=O) [C@H]5N6[C@] (CC5) (CCN (C (OC) =O) C[C@H] (NC (=O) C7=CC=8C (S7) =CC=C (C (P (=O) (O) O) (F) F) C8) C6=O) [H]) CCC (N) =O) =O) =O) CC3) =CC2) C9C (=O) NC (=O) CC9
Molecular Formula
C58H63F4N10O14PS
Molecular Weight
1263.21
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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