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LNK2-S

LNK2-S is a cleavable linker-toxin conjugate, specifically linking the potent topoisomerase I inhibitor Exatecan, for the construction of antibody-drug conjugates (ADCs) . It is a key intermediate used in research for developing and evaluating novel ADC therapeutics in both in vitro and in vivo experimental models.

Product Specifications

CAS Number

2983134-61-6

Smiles

N (C (O[C@H] (CNC (CC[C@@H] (C (N (CC (N (CC (N (CC (N (CC (N (CC (N (CC (N (CC (N (CC (N (CC (N (CC (N) =O) C) =O) C) =O) C) =O) C) =O) C) =O) C) =O) C) =O) C) =O) C) =O) C) =O) NC (COCCOCCNC (CCN1C (=O) C=CC1=O) =O) =O) =O) C2=CC (N (=O) =O) =C (O[C@@H]3O[C@H] (C (O) =O) [C@@H] (O) [C@H] (O) [C@H]3O) C=C2) =O) [C@@H]4C5=C6C (C=7N (C6) C (=O) C8=C (C7) [C@] (CC) (O) C (=O) OC8) =NC=9C5=C (CC4) C (C) =C (F) C9

Molecular Formula

C87H112FN19O33

Molecular Weight

1970.93

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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