PF-1367550
PF-1367550 is a pan-JAK inhibitor that potently suppresses the release of the chemokines CXCL9, CXCL10, and CXCL11 from primary airway epithelial cells. This activity makes it a useful research tool for investigating JAK/STAT signaling and related inflammatory pathways in respiratory disease models, both in vitro and in vivo.
Product Specifications
CAS Number
319461-60-4
Field of Research
Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology
Smiles
OC=1C=CC (C=2C=CC=3C (=NNC3C2) C4=NC=5C=CC=CC5N4) =C (C1) CC
Molecular Formula
C22H18N4O
Molecular Weight
354.41
Storage Conditions
-20°C
Notes
For research use only.
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