PF-1367550

PF-1367550 is a pan-JAK inhibitor that potently suppresses the release of the chemokines CXCL9, CXCL10, and CXCL11 from primary airway epithelial cells. This activity makes it a useful research tool for investigating JAK/STAT signaling and related inflammatory pathways in respiratory disease models, both in vitro and in vivo.