DMT-2′Fluoro-dU Phosphoramidite

DMT-2’ Fluoro-dU Phosphoramidite (2'-F-dU Phosphoramidite) is a uridine phosphoramidite with a fluorine in the 2’ position. DMT-2’ Fluoro-dU Phosphoramidite could be used for nucleoside modification and synthesis of DNA[1].

Product Specifications

CAS Number

[146954-75-8]

Product Name Alternative

2'-F-dU Phosphoramidite

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Nucleoside Antimetabolite/Analog

Type

Oligonucleotides

Related Pathways

Cell Cycle/DNA Damage

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/dmt-2-fluoro-du-phosphoramidite.html

Purity

99.98

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

F[C@@H]1[C@H](OP(OCCC#N)N(C(C)C)C(C)C)[C@@H](COC(C2=CC=C(OC)C=C2)(C3=CC=C(OC)C=C3)C4=CC=CC=C4)O[C@H]1N5C(NC(C=C5)=O)=O

Molecular Formula

C39H46FN4O8P

Molecular Weight

748.78

Precautions

H302, H315, H319, H335

References & Citations

[1]Y. Dantsu, et al., (2021) Synthesis of 2′-Deoxy-2′-fluoro-L-cytidine and Fluorinated L-Nucleic Acids for Structural Studies, ChemistrySelect, 6, 10597.