CDK7-IN-31
CDK7-IN-31 is a potent, orally bioavailable small molecule inhibitor of cyclin-dependent kinase 7 (CDK7) with a Kd of 0.18 nM. It is a valuable research tool for investigating CDK7's role in transcription and cell cycle progression, demonstrating anticancer activity in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
2943043-62-5
Field of Research
Cell Biology, Epigenetics & Chromatin, Pharmacology & Drug Discovery
Smiles
P (C) (C) (=O) C1=C2C=3C (C4=C (C (F) (F) F) C=NC (N4) =N[C@@]5 (C[C@] (CC5) (N (C) CCC (F) (F) CN (C) C (=O) C1=CC3) [H]) [H]) =CN2
Molecular Formula
C27H32F5N6O2P
Molecular Weight
598.55
Storage Conditions
-20°C
Notes
For research use only.
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