MG-B-28
MG-B-28 is a small molecule inhibitor of the BTLA-HVEM immune checkpoint interaction with an IC50 of 906 nM. By blocking this pathway, it enhances T cell activation in vitro, making it a useful research tool for investigating immuno-oncology and autoimmune mechanisms.
Product Specifications
Field of Research
Cell Biology, Metabolism Research
Smiles
COC1=CC=C ([C@@H] (C#N) N2CCN (C (C (C3=C4C=CC=C3) =NN (C5=CC=CC=C5) C4=O) =O) CC2) C=C1
Molecular Formula
C28H25N5O3
Molecular Weight
479.53
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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