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VU6043653

VU6043653 is a potent, selective, and brain-penetrant negative allosteric modulator of the mGlu5 receptor, exhibiting an IC50 of 325 nM at the human receptor. It is a valuable research tool for investigating mGlu5 function in neurological and psychiatric disorders, suitable for both in vitro binding assays and in vivo behavioral studies.

Product Specifications

CAS Number

3032791-06-0

Field of Research

Cell Biology, Epigenetics & Chromatin, Molecular Biology, Signal Transduction, Stem Cell & Developmental Biology

Smiles

O=C (NC1=NC=C (F) C=C1) C=2N=C (C=C (OC=3C=NN (C3) C) C2) C

Molecular Formula

C16H14FN5O2

Molecular Weight

327.31

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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