ROCK/HDAC-IN-1
ROCK/HDAC-IN-1 (Compound 10h) is an orally active dual inhibitor of ROCK1/2 and HDAC1/2/3/6/8. It demonstrates potent antiproliferative activity in breast cancer cells, induces immunogenic cell death markers like CRT and HMGB1, and shows in vivo antitumor efficacy with T cell activation and low toxicity.
Product Specifications
Field of Research
Cell Biology, Epigenetics & Chromatin, Molecular Biology, Signal Transduction, Stem Cell & Developmental Biology
Smiles
O=C (NCCCCCCC (NO) =O) C1=CC2=CC (C3=CNN=C3) =CC=C2S1
Molecular Formula
C19H22N4O3S
Molecular Weight
386.47
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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