MG-T-19
MG-T-19 is a potent small molecule TIM-3 inhibitor (K_D=0.26 μM) that blocks interactions with PtdSer, CEACAM1, and Gal-9. This blockade enhances TNF-α and IFN-γ production in PBMCs, restoring T-cell-mediated anti-tumor activity, supporting its use in immuno-oncology research both in vitro and in vivo.
Product Specifications
CAS Number
328540-44-9
Product Name Alternative
MGT-19, MG T19
Field of Research
Immunology & Inflammation
Purity
98.30% (May vary between batches)
Smiles
O=C (NC1=CC (Cl) =CC=C1O) C2=NN3C (N=C (C=C3C (F) (F) F) C=4SC=C (Br) C4) =C2Br
Molecular Formula
C18H8Br2ClF3N4O2S
Molecular Weight
596.6
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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