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MG-T-19

MG-T-19 is a potent small molecule TIM-3 inhibitor (K_D=0.26 μM) that blocks interactions with PtdSer, CEACAM1, and Gal-9. This blockade enhances TNF-α and IFN-γ production in PBMCs, restoring T-cell-mediated anti-tumor activity, supporting its use in immuno-oncology research both in vitro and in vivo.

Product Specifications

CAS Number

328540-44-9

Product Name Alternative

MGT-19, MG T19

Field of Research

Immunology & Inflammation

Purity

98.30% (May vary between batches)

Smiles

O=C (NC1=CC (Cl) =CC=C1O) C2=NN3C (N=C (C=C3C (F) (F) F) C=4SC=C (Br) C4) =C2Br

Molecular Formula

C18H8Br2ClF3N4O2S

Molecular Weight

596.6

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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