PROTAC BTK Degrader-11
PROTAC BTK Degrader-11 is a potent, small molecule PROTAC that induces degradation of Bruton's tyrosine kinase (BTK) with a DC50 of 1.7 nM. It is a valuable chemical tool for investigating BTK-dependent signaling in oncology research, applicable in both cellular and in vivo studies of B-cell malignancies.
Product Specifications
CAS Number
2736508-94-2
Field of Research
Cardiovascular Research, Cell Biology, Pharmacology & Drug Discovery, Signal Transduction
Smiles
CC=1C=C (C2=C3C (NC (=C3) C=4C=CC (=NC4) N5CCN (CC6CCN (CC6) C7=CC=C (C=C7) C8C (=O) NC (=O) CC8) CC5) =NC=N2) C=CC1[C@H] (NC (=O) C9=NC (C (C) (C) C) =NO9) C
Molecular Formula
C48H55N11O4
Molecular Weight
850.02
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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