TH023
TH023 is a small molecule inhibitor that selectively disrupts TLR4 homodimerization, blocking downstream NF-κB activation and inflammatory cytokine production. It demonstrates potent anti-inflammatory activity in cellular assays and in vivo models, including LPS-induced sepsis and acute lung injury, making it a valuable research tool for studying innate immunity and inflammation-related diseases.
Product Specifications
Field of Research
Immunology & Inflammation, Neuroscience, Pharmacology & Drug Discovery, Signal Transduction
Molecular Formula
C22H21ClF2N4O
Molecular Weight
430.88
Storage Conditions
-20°C
Notes
For research use only.
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