YAP/TAZ-TEAD-IN-2
YAP/TAZ-TEAD-IN-2 (Compound 51) is a potent, nanomolar inhibitor of the YAP/TAZ-TEAD protein-protein interaction, blocking downstream oncogenic transcription. It effectively reduces target gene expression (e.g., Cyr61, CTGF) and inhibits breast cancer cell proliferation in vitro, making it a valuable chemical probe for Hippo pathway and cancer research.
Product Specifications
Field of Research
Cancer Biology, Cell Biology, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology
Smiles
C=CS (NCCN (C=C1) C (C1=C2) =CC=C2OCC3=CC=CC=C3) (=O) =O
Molecular Formula
C19H20N2O3S
Molecular Weight
356.44
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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