PfCLK3-IN-1
PfCLK3-IN-1 (Compound 4) is a covalent PfCLK3 inhibitor active under alkaline conditions (pEC50 7.1) . It blocks gametocyte maturation to prevent malaria transmission and inhibits parasite growth in vitro (IC50 239.5 nM against Dd2-B2 clone), supporting research in antimalarial drug discovery.
Product Specifications
Field of Research
Infectious Disease & Virology, Metabolism Research, Pharmacology & Drug Discovery
Smiles
OC (C (C=C1) =CC=C1C2=C (C=C (C3=CC (CN4CCN (C (CCl) =O) CC4) =CC=C3OC) N5) C5=NC=C2) =O
Molecular Formula
C28H27ClN4O4
Molecular Weight
518.99
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
BT-AP00787-03 100 µL
BID (Cleaved-Arg71) Rabbit Polyclonal Antibody
Sign In for Pricing
View Details VAng-Yyj3002-500gEcoli 500 µg (E. coli)
Recombinant Mycobacterium Bovis Mb0988c Protein (aa 1-266)
Sign In for Pricing
View Details