Tesevatinib tosylate
Tesevatinib tosylate (XL-647 tosylate) is an orally bioavailable, brain-penetrant multi-kinase inhibitor targeting EGFR, HER2, VEGFR2, and Src. It demonstrates potent antitumor activity in glioblastoma models in vitro and has shown efficacy in preclinical in vivo studies for cancers including NSCLC and glioblastoma.
Product Specifications
CAS Number
1000599-06-3
Field of Research
Cardiovascular Research, Signal Transduction
Smiles
S (=O) (=O) (O) C1=CC=C (C) C=C1.N (C=1C2=C (C=C (OC[C@@H]3C[C@]4 ([C@@] (C3) (CN (C) C4) [H]) [H]) C (OC) =C2) N=CN1) C5=C (F) C (Cl) =C (Cl) C=C5
Molecular Formula
C31H33Cl2FN4O5S
Molecular Weight
663.59
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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