FK-888
FK-888 is a selective, high affinity tachykinin NK1 receptor antagonist (Ki = 0.69 nM) that displays 320-fold selectivity for human over rat NK1 receptors. FK-888 inhibits substance P-induced contraction of isolated guinea pig trachea (IC50 = 32 nM) and inhibits substance P-induced airway constriction in vivo.
Product Specifications
CAS Number
138449-07-7
Purity
0.98
Smiles
OC1CN (C (C2C3C (=CC=CC=3) N (C) C=2) =O) C (C (NC (C (N (C) CC2C=CC=CC=2) =O) CC2C=CC3C (=CC=CC=3) C=2) =O) C1
Molecular Formula
C36H36N4O4
Molecular Weight
588.69544
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS9002196 Inquire
Rabbit anti-Escherichia coli O6:H1 (strain CFT073/700928/UPEC) RSXC Polyclonal Antibody
Sign In for Pricing
View Details 