What is the catalog number for Agnuside?

The catalog number for Agnuside is HY-N2518.

What sizes are available for Agnuside?

Agnuside is available in the following size(s): 1 mg, 5 mg, 10 mg.

How many pack sizes does Agnuside come in?

Agnuside is available in 3 different pack sizes.

Is Agnuside in stock?

Agnuside is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Agnuside?

Agnuside is manufactured by QuantiMol.

What is the estimated delivery time for Agnuside?

Estimated delivery time for Agnuside is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Agnuside?

The safety data sheet for Agnuside is available here: http://file.medchemexpress.com/batch_PDF/HY-N2518/Agnuside-SDS-MedChemExpress.pdf.

Agnuside

Agnuside is used in the study of asthma, inflammation, and angiogenic diseases. Agnuside is an orally active compound that can be extracted from Vitex negundo[1][2][3][4].

Product Specifications

CAS Number

11027-63-7

Product Name Alternative

Agnoside

UNSPSC

12352005

Hazard Statement

H302

Target

ASCT; Caspase; COX; HIF/HIF Prolyl-Hydroxylase; NO Synthase

Type

Natural Products

Related Pathways

Apoptosis; Immunology/Inflammation; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Inflammation/Immunology; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/agnuside.html

Purity

99.90

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

OC[C@H]([C@@H](O)[C@H](O)[C@H]1O)O[C@@]1([H])O[C@H]2[C@@]3([H])[C@](C=CO2)([H])[C@H](O)C=C3COC(C4=CC=C(O)C=C4)=O

Molecular Formula

C22H26O11

Molecular Weight

466.44

Precautions

H302

References & Citations

[1]Tirpude NV, et al. Agnuside mitigates OVA-LPS induced perturbed lung homeostasis via modulating inflammatory, autophagy, apoptosis-fibrosis response and myeloid lineages in mice model of allergic asthma. Int Immunopharmacol. 2022 May;106:108579. |[2]Le DD, et al. Iridoid derivatives from Vitex rotundifolia L. f. with their anti-inflammatory activity. Phytochemistry. 2023 Jun;210:113649.|[3] Pillarisetti P, Myers KA. Identification and characterization of agnuside, a natural proangiogenic small molecule. Eur J Med Chem. 2018 Dec 5;160:193-206.|[4]Zhang L, et al. Agnuside Alleviates Synovitis and Fibrosis in Knee Osteoarthritis through the Inhibition of HIF-1α and NLRP3 Inflammasome. Mediators Inflamm. 2021 Mar 16;2021:5534614.