A-770041
A-770041 is a selective, orally bioavailable Lck inhibitor that suppresses IL-2 production in stimulated whole blood and prevents cardiac allograft rejection. It also attenuates pulmonary fibrosis by reducing TGF-β from regulatory T cells, making it a research tool for studying immunology and fibrosis in vitro and in vivo.
Product Specifications
CAS Number
869748-10-7
Product Name Alternative
Rat, selective, Src, small-molecule, T cell, acute rejection, A770041, A-770041, A 770041, concanavalin A, IL-2, Lck
Field of Research
Cardiovascular Research, Signal Transduction
Purity
99.23% (May vary between batches)
Solubility
DMSO:20 mg/mL (32.17 mM)
Smiles
NC1=C2C (=NN (C2=NC=N1) [C@H]3CC[C@@H] (CC3) N4CCN (C (C) =O) CC4) C5=CC (OC) =C (NC (=O) C6=CC=7C (N6C) =CC=CC7) C=C5
Molecular Formula
C34H39N9O3
Molecular Weight
621.73
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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