MF63
MF63 is a potent and selective inhibitor of microsomal prostaglandin E synthase-1 (mPGES-1), demonstrating low nanomolar IC50 values against both porcine and human enzymes. This small molecule is a valuable research tool for investigating the role of PGE2 in inflammation, pain, and fever, with utility in both in vitro biochemical assays and in vivo disease model studies.
Product Specifications
CAS Number
892549-43-8
Product Name Alternative
MF 63, MF63, MF-63
Field of Research
Immunology & Inflammation
Purity
99.91% (May vary between batches)
Solubility
DMSO:43 mg/mL (113.51 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.28 mM)
Smiles
Clc1ccc2c3[nH]c (nc3c3ccccc3c2c1) -c1c (cccc1C#N) C#N
Molecular Formula
C23H11ClN4
Molecular Weight
378.81
Storage Conditions
-20°C
Notes
For research use only.
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