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SJYHJ-026

SJYHJ-026 (compound 37) is a potent and selective PXR degrader, achieving 66.4% degradation with a DC50 of 86.6 nM. It exhibits cytotoxic activity in SNU-C4 HiBiT-PXR KI cells, with IC50 values of approximately 98 μM. This tool compound is useful for investigating PXR's role in drug metabolism and cancer biology in vitro.

Product Specifications

Field of Research

Pharmacology & Drug Discovery

Molecular Formula

C60H84N8O11S

Molecular Weight

1125.42

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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