SJYHJ-026
SJYHJ-026 (compound 37) is a potent and selective PXR degrader, achieving 66.4% degradation with a DC50 of 86.6 nM. It exhibits cytotoxic activity in SNU-C4 HiBiT-PXR KI cells, with IC50 values of approximately 98 μM. This tool compound is useful for investigating PXR's role in drug metabolism and cancer biology in vitro.
Product Specifications
Field of Research
Pharmacology & Drug Discovery
Molecular Formula
C60H84N8O11S
Molecular Weight
1125.42
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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