Antibiofilm agent-13

Antibiofilm agent-13 is a broad-spectrum antibacterial small molecule that disrupts bacterial cell membranes, leading to transmembrane potential loss, ROS generation, and cellular content leakage. It exhibits potent activity against Gram-positive (MIC 0.5-1 μg/mL) and Gram-negative bacteria (MIC 1-32 μg/mL), making it suitable for in vitro biofilm and antimicrobial mechanism studies.