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DBCO-PEG3-VC-Exatecan

DBCO-PEG3-VC-Exatecan (compound 25) is an ADC drug-linker conjugate featuring the topoisomerase I inhibitor Exatecan. It is used in the research and development of antibody-drug conjugates for targeted cancer therapy, with applications in both in vitro cytotoxicity assays and in vivo preclinical tumor model studies.

Product Specifications

CAS Number

2754384-70-6

Field of Research

Molecular Biology, Pharmacology & Drug Discovery; Cell Biology

Smiles

N (C (OCC1=CC=C (NC ([C@@H] (NC ([C@@H] (NC (CCOCCOCCOCCNC (CCC (=O) N2C=3C (C#CC=4C (C2) =CC=CC4) =CC=CC3) =O) =O) [C@@H] (C) C) =O) CCCNC (N) =O) =O) C=C1) =O) [C@@H]5C6=C7C (C=8N (C7) C (=O) C9=C (C8) [C@] (CC) (O) C (=O) OC9) =NC=%10C6=C (CC5) C (C) =C (F) C%10

Molecular Formula

C71H79FN10O15

Molecular Weight

1331.44

Storage Conditions

-20°C

Notes

For research use only.

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