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PROTAC SMARCA2/4-degrader-34

PROTAC SMARCA2/4-degrader-34 (compound 38) is a potent, dual degrader of SMARCA2 and SMARCA4 proteins. It also binds to and reduces 3xFLAG-PXR expression with a DC50 of 85.1 nM, making it a valuable chemical probe for studying chromatin remodeling and nuclear receptor biology in cellular models.

Product Specifications

Field of Research

Epigenetics & Chromatin, Neuroscience, Pharmacology & Drug Discovery

Molecular Formula

C58H78N8O13S

Molecular Weight

1127.35

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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