WEE1-IN-11
WEE1-IN-11 (Compound 13) is a highly potent and selective CDK2 inhibitor (IC50 = 2.0 nM) . It demonstrates robust anti-proliferative activity in various cancer cell lines, including NCI-H446, A427, OVCAR3, C33A, and WiDr. This inhibitor is a valuable chemical probe for studying cell cycle regulation and oncology research in vitro.
Product Specifications
CAS Number
2975172-98-4
Field of Research
Cancer Biology, Cell Biology
Smiles
N (C=1N=C (C (=CN1) C2=CN=CS2) C=3SC (=NC3) N4CC[C@H] (F) C4) C5=CC (OC) =C (C=C5) N6CCN (C) CC6
Molecular Formula
C26H29FN8OS2
Molecular Weight
552.69
Storage Conditions
-20°C
Notes
For research use only.
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