IL-17A inhibitor 4
Example 449 is a potent small molecule IL-17A inhibitor, demonstrating IC50 values of 0.028 μM in an HTRF assay and 0.0047 μM in NHK cells. This compound is a valuable research tool for studying IL-17A biology in both biochemical and cellular contexts, applicable to autoimmune and inflammatory disease research.
Product Specifications
CAS Number
2735650-99-2
Field of Research
Immunology & Inflammation, Immunology & Inflammation; Pharmacology & Drug Discovery
Smiles
C (NC (C[C@@H]1C (F) (F) C1) =O) (C2 (C#N) CCC2) C3=CC=4N (N=C3) C=C ([C@@H] (NC (=O) C=5C (=NON5) C6CC6) C7CCC (F) (F) CC7) N4
Molecular Formula
C30H32F4N8O3
Molecular Weight
628.62
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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043671 200 µL
USP4, NT (USP4, UNP, UNPH, Ubiquitin carboxyl-terminal hydrolase 4, Deubiquitinating enzyme 4, Ubiquitin thioesterase 4, Ubiquitin-specific-processing protease 4, Ubiquitous nuclear protein homolog)
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