C-Kit-IN-8
C-Kit-IN-8 (Compound 53) is a c-Kit kinase inhibitor with an IC50 >1 μM against uKIT. It also suppresses proliferation of wild-type and mutant GIST430 and BaF3 cancer cell lines with IC50 values >0.1 μM. This inhibitor is a useful research tool for studying c-Kit-dependent signaling in gastrointestinal stromal tumors (GIST) and hematological cancers in vitro.
Product Specifications
CAS Number
2941024-89-9
Field of Research
Signal Transduction
Smiles
O=C (NC1=CC=C (C=C1) NC=2N=CN=C3C=C (OCCOC) C=C (F) C32) CCN4C (=O) CCC4
Molecular Formula
C24H26FN5O4
Molecular Weight
467.49
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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