JMS-175-2
JMS-175-2 is a potent small molecule inhibitor of the BRCC36 isopeptidase complex (BRISC) with an IC50 of 3.8 μM. It serves as a valuable research tool for investigating Type I interferon-mediated diseases, enabling both in vitro biochemical studies and in vivo models of autoimmunity and inflammation.
Product Specifications
CAS Number
3042887-70-4
Field of Research
Cell Biology, Epigenetics & Chromatin, Molecular Biology, Protein Biochemistry
Smiles
O=C (NC1CCNCC1) C2=NN (C=C2NC (=O) C=3C (Cl) =CC=CC3Cl) C (=O) C=4C (Cl) =CC=CC4Cl
Molecular Formula
C23H19Cl4N5O3
Molecular Weight
555.24
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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