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PROTAC EZH2 Degrader-3

PROTAC EZH2 Degrader-3 (ZJ-20) is a potent, cell-permeable small molecule that selectively degrades EZH2 and disrupts PRC2 complex function, reducing H3K27me3 levels. It demonstrates robust anti-proliferative effects in vitro by inducing G0/G1 cell cycle arrest and apoptosis, making it a valuable chemical probe for oncology and epigenetics research.

Product Specifications

Field of Research

Cell Biology, Epigenetics & Chromatin, Pharmacology & Drug Discovery

Molecular Formula

C56H68N8O8

Molecular Weight

981.19

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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