NLRP3-IN-58
NLRP3-IN-58 (DS15) is a small molecule inhibitor of the NLRP3 inflammasome, exhibiting an IC50 of 3.85 μM. At 10 μM, it suppresses IL-1β release by 33%. This compound is a useful research tool for studying NLRP3-driven inflammation in cellular models and related disease mechanisms.
Product Specifications
CAS Number
2956014-05-2
Field of Research
Cell Biology, Immunology & Inflammation
Smiles
O=C (NC1=CC=CC (=C1) S (=O) (=O) NC=2C=CC=CC2) CC3=CNC=4C=C (Cl) C=CC43
Molecular Formula
C22H18ClN3O3S
Molecular Weight
439.92
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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