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NLRP3-IN-58

NLRP3-IN-58 (DS15) is a small molecule inhibitor of the NLRP3 inflammasome, exhibiting an IC50 of 3.85 μM. At 10 μM, it suppresses IL-1β release by 33%. This compound is a useful research tool for studying NLRP3-driven inflammation in cellular models and related disease mechanisms.

Product Specifications

CAS Number

2956014-05-2

Field of Research

Cell Biology, Immunology & Inflammation

Smiles

O=C (NC1=CC=CC (=C1) S (=O) (=O) NC=2C=CC=CC2) CC3=CNC=4C=C (Cl) C=CC43

Molecular Formula

C22H18ClN3O3S

Molecular Weight

439.92

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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