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MZ82

MZ82 is a potent and brain-penetrant ABCG2/BCRP inhibitor (IC50 ~23 nM), derived from Ko 143. It demonstrates superior metabolic stability in liver microsomes and improved in vivo performance in mice, making it a valuable tool for studying drug efflux and pharmacokinetics in cancer and neuroscience research.

Product Specifications

Field of Research

Pharmacology & Drug Discovery

Molecular Formula

C26H29N3O3

Molecular Weight

431.53

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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